Thursday, April 27, 2023

7 Momentous Inventions Discovered by Accident

 

  7 Momentous Inventions Discovered by Accident





Penicillin


           The world’s first antibiotic, which has prevented millions of deaths from infection and disease, was the accidental byproduct of a messy workspace.

Alexander Fleming, a bacteriologist in London, returned from a vacation in 1928 to discover that one of the petri dishes in his lab had mold growing on it— the result of unintended contamination. On closer inspection, he saw that the area around the mold was free of bacteria. Fleming named this bacteria-killing mold juice penicillin after the species of fungus, Penicillium notatum, and published a paper about his discovery in 1929. However, he wasn’t sure if it had any practical use, as it was difficult to purify and stabilize.


         A decade later, chemists at Oxford University read Fleming’s paper and took up the project of turning penicillin into viable medicine. It was first tested on a patient in 1940, and widespread use began in 1942. Today, penicillin is the most commonly-used antibiotic in the world.


Smoke Detectors


    Smoke detectors are so commonplace in homes and businesses that they’re easy to overlook. But their invention has saved millions of lives, and having a working smoke detector in the home decreases the risk of dying in a fire by more than half. For that, you can thank Swiss physicist Walter Jaeger. In the 1930s, Jaeger was trying to invent a sensor that could detect poison gas. Instead, his device registered the smoke from his cigarette— a discovery that led to the invention of the modern smoke detector.





Wednesday, April 19, 2023

Nifty bulls may raise a toast in June quarter

Nifty bulls may raise a toast in June quarter 


             The new financial year has begun on a good note for domestic equities as benchmark indices gained in 7 of the 8 trading sessions in the ongoing quarter, on the back of consistent buying by foreign institutional investors.





             Historical data shows that the first quarter of the financial year has by and large been positive for Dalal Street. The positive start to the quarter this time has, therefore, brightened prospects for the history to repeat itself.


            In the June quarter of 2020, the 50-stock index gained a whopping 20% as investors rejoiced the re-opening of the economy from the Covid-19 pandemic-induced lockdown. The June quarter of 2020 was the second best in terms of returns for the market in the last 15 years.

Historical returns of Nifty 50 in June quarter


             Some stability in the global markets and a surprise move by the Reserve Bank of India to pause interest rate hikes earlier this month brought a relief rally in the market, with the Nifty 50 gaining a little over 5% in the last 10 odd sessions.





            
          “The markets might be inching up but it is time to be cautious. There is still more pain to come and this is not the time to be aggressive with equity allocation,” Chanda said.

Staff Scientist – Murine Phenotyping Core

 

Staff Scientist – Murine Phenotyping Core

Environment:

The MPC is a full scale, busy, and in demand mouse phenotyping core that provides technical and scientific expertise for the phenotypic characterization of mouse models. We place a strong emphasis on scientific collaboration, technical skill, customization of model specific testing strategies, and innovative growth and development. We collaborate on projects with investigators across NIH on a diversity of mouse models utilizing state of the art equipment and comprehensive testing methodologies to assess multiple physiological and behavioral systems. The core is equipped to handle all aspects of comprehensive, complex, and diverse phenotyping projects in the areas of cardiovascular, metabolic, pulmonary, neuromuscular, behavioral phenotyping and exercise physiology testing while providing scientific consultation and collaboration with NIH research labs. The position offers diverse and exciting opportunities for interdisciplinary collaboration, development of comprehensive expertise in mouse phenotyping and comparative medicine, the ability to shape and steer ongoing growth of the core, and to conduct independent research.

Position role:

The core seeks motivated candidate to assist in both the technical, and scientific aspects involved in the core’s daily work and collaborations, and to promote continued growth and contributions towards the core’s reputation of excellence and knowledge in the field of phenotyping mouse models that researchers across NIH seek out.

Areas of potential growth:

The successful candidate will have the exciting opportunity to help steer and promote the continued growth of the core as a state-of-the-art mouse phenotyping center, including the continued initiation and application of new techniques and methods, learning new equipment, and facility design/planning as the core continues to expand, etc. 

Current Core Testing methodologies: 

The MPC houses the largest and most diverse repertoire of mouse testing equipment and systems at the NIH and has built up the most robust and comprehensive testing methodologies available anywhere for investigating scientific inquiry involving diverse mouse models. 

Epidermis | Dermis | Subcutaneous layer | Cells in the skin

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